The Hilton Cartagena offers a well situated position for guests of all purposes to the area. Both the Caribbean beaches and the historic city center are very close to the property, and this means that leisurely guests are afforded a plethora of shopping, nightlife, dining, and entertainment options along the foot tour. Other nearby attractions include the City Wall, Crespo, Palcio De La Inquisicion, Plaza Bolivar, San Filipe De Barajas Castle, and many bicycle and foot touring areas. Those in town on business are within minutes of the government complexes and corporate headquarters housed in Cartagena de Indias and neighboring cities. Car parking is offered at the Hilton Cartagena, and the airport stands just a few miles away.

There are many amenities available at the Hilton Cartagena, including wireless Internet access, cable television, valet laundry, some views, room service, and direct-dial telephones.

Dining at the Hilton Cartagena consists of two signature restaurants. The hotel also has a swimming pool and whirlpool, a fitness center, a bar and lounge, a fitness center and sport courts, and ample business and meeting facilities.